On shake days, you’ll use IsaLean meal replacement shakes for two meals a day, and then eat a third meal of around 500 calories, which you make yourself. Shakes are between 240 and 280 calories, approximately half of what I’d call an actual meal. If you get hungry, which you most likely will, you can treat yourself with an Isagenix snack like 100-calorie Slim Cakes, which look like little turds. Doesn’t that sound like fun? Yum yum!

In no way am I challenging any of the research you have done or your claims about the ingredients, etc. Your science is solid. What I am challenging is the “for whom” aspect of the article that was not considered. Is Isagenix much healthier, and a better food choice for 99% of the people who consume it? Yes, because most of them are overweight and undereducated about food. Is Isagenix better than a balanced, nutrient rich meal composed of whole foods that are free of any processed ingredients, chemicals, preservatives, additives, isolates, etc. Yes.


Cleansing is one of the many reasons that Isagenix systems are different from other “diets”. In fact, diet is really the wrong word to use to describe Isagenix. We offer a collection of systems that can be customized to your own health goals and adopted as a lifestyle, meaning these are habits and tools you’ll have for the long haul. Cleansing is one of those habits within an Isagenix lifestyle.
I come from a background of clean eating, working out, medical, etc. and someone who suffers from a huge list of medical issues and am on about 30 medications. I decided to try Isagenix because I want to have some energy so I can be a mom again to my two young children and maybe lose the 35 pounds I have gained since being diagnosed with psoriatic arthritis, fibro, heart problems, etc. etc. etc. I also just turned 40 and it was time for a change. I started Isagenix last week and I tell you that it is like I just woke up. My clarity is scary amazing, I smell the trees, I see the colors, I hear things, I am remembering stuff from years ago. I have chronic fatigue syndrome, could sleep all day and then sleep 12 to 14 hours a night. I now have a hard time going to bed and I am getting tons done around our house and I go out with my family. Thanks to Isagenix for giving me a life and getting off of meds hopefully and back to working out.

This is my unbiased comment about Isagenix. First, let me give you a quick background. I have always eaten healthy and exercised than the past few months happened. 1) We had the worst winter I have ever experienced… hubby and I ate a lot of comfort food. 2) I broke one ankle and sprained another hiking in March. 3) blood clot formed in my leg broke of and went into my lungs causing a bi-lateral embolism which almost killed me. 4) I quit smoking. Between the terrible winter, in-mobility (two bad ankles), hospital and recovery time and letting go of my nasty habit… I was at the heaviest weight I have ever been at.
Funny how you’ve asked this question a dozen times and no one can answer it. I did the same thing on their Facebook page months ago and all anyone could say was that the multi vitamins were all whole food and Isagenix didn’t use anything synthetic. Lie. I was also told that they’re not certified organic because they get products from all over the world, some countries which do not certify. So if that’s the case, label the products with the ingredients that apparently ARE organic. The ingredients you’ve listed are not healthy, I’m sure some of the ingredients are… but seeing as the people consuming these products are most likely coming from a diet of McDonalds – they believe it’s healthy. They should get it right and say it’s healthIER than the crap they used to eat.

1/4 an apples worth of fructose per shake is nothing, my family has grown apples locally for over 100 years and we are often eating over 6 per day ALL YEAR ROUND, that’s a dozen shakes worth 365 days a year, now obviously there are a lot of factors involved, but JUST that alone suggests that there is more going on, my family all live into their 90’s or older, I doubt that eating that amount of fructose is deleterious to our health. And yes an apple is different then fructose alone…I’m just talking about the sugar amount.


Harriet Hall, MD, a retired Air Force physician and flight surgeon, writes and educates about pseudoscientific and so-called alternative medicine. She is a contributing editor and frequent contributor to the Skeptical Inquirer and contributes to the blog Science-Based Medicine. She is author of Women Aren’t Supposed to Fly: Memoirs of a Female Flight Surgeon and coauthor of the 2012 textbook Consumer Health: A Guide to Intelligent Decisions.
Either you are getting bad advice from your coach or you are not doing the program correctly, my wife and I have been on Isagenix for over 2 years have lost weight and have never been healthier, there is no reason why you should be hungry you can do your shakes plus your meals make sure taking in enough calories, if your not happy you send your products back and you will get your money back they offer a great money back guarantee. Most that fail on this program either have bad coaching or are not being honest with themselfs and are not doing the program correctly
The undenatured Reserveage whey protein Dani shows in the video is a poorer copy of ingredients as used in Isagenix Whey Protein and is more expensive. Isagenix use undenatured Whey and has lactase added for digestion. Reserveage has only started in 2008 using same natural supplements as what Isagenix have been producing. How is it ethical to knock the original and promote the newcomer?

I just wanted to thank you for your review of Isagenix. I have been doing some research because some close friends have been pushing this product on me. However, with both parents as personal trainers and a history of being in top shape, I know that this is not the right choice. I’m too nice to let my friends down without some real facts to back up my reasons why and your review gave me a lot to work with!
Thank you for posting this. I find it deeply disturbing how Isagenix consultants try to tell you how no other food on the planet has as many nutrients. The whey made my skin have terrible and painful acne flareups and the Isagenix Natural Accelerator made me unable to sleep for days. Neither my Isagenix consultant or the company representative I spoke with were honest about their products giving people such side effects. Instead they tried to tell me I had acne before and must be under stress for my job so that’s why I can’t sleep. This is all a pyramid scheme, where they want to make you a lifer while screwing up your digestive system by not giving people the opportunity to let their bodies digest real foods and not processed powder.
So I signed up for the 30 day cleanse and lasted 3 days…my stomach couldn’t take the shakes and other supplements. I have since sent back my stuff and am waiting for a refund. Meanwhile I am feeling disappointed in my PT who recommended this stuff. 11g of sugar per shake? Sunflower oil? Time to find a new PT! Thanks for this article…wish I had seen it a month ago! 🙂
One last thing……….. too many people are rude and arrogant to others that we do not even know. We sit at home and watch the news at night and are appalled at some of this things that happen in our time. Everyone says, I wish there was something we could do. Well, there is. Try not bagging others for their opinion, espcially those we do not know. It only shows how base some people can be. Keep in mind, that this lady is offering free advice, which I will be taking.
If you want to lose weight, eat less than you burn, full stop. Learn to cook and eat stuff you make yourself. Don’t waste your money on organic either, as if anything the anti-GMO movement is even scammier than Isagenix. Teach yourself enough biology and chemistry to understand why these are scams. And most of all, accept that successful weight loss takes time. It’s a long-term project; don’t rush it, or buy into shortcuts.
Quite a stimulating thread you have here! I just found your site doing some other research and stumbled upon it. I use Isagenix products (among others…of course, there are other fine products out there) in my nutritional regimen. My mother has been taking their flagship product, Product B for a couple years now. During this time (after 1 1/2 yrs), she was able to get off virtually all her medications for pain from a spinal condition and a digestive condition. Product B was the only new thing she introduced in her daily regimen. She feels younger and has more energy than before. She is now 93. But, this is mainly what I wanted to clarify. Your call regarding your question about their products being certified as GMO free. I made a similar call myself early on asking if their ingredients are all organic. (At the time, I was inquiring just about Product B). I was given a more in depth answer than you were. I was told that some of their ingredients are sourced from outside of the U.S. where other countries don’t have the same organic certification process that we have here, so it would not be possible to declare them as “certified” organic. However, she gave me their very detailed site where it declared that the step-by-step process for PB met or surpassed organic standards. As an example, the co-founder and master formulator, master botanist and master herbalist, John Anderson, happens to own land in the Himalayas where his herbs that he uses for PB are very well protected at their pristine source. So, unfortunately, when getting answers from a customer service individual, sometimes they may be just the short answer, the one you might want to hear, but not the whole answer. Also, correct me if I’m wrong, but my understanding is that if something is organic, it is not allowed to be GMO.
The Isagenix 30-day plan replaces two meals per day with shakes and has you eat a 400- to 600-calorie meal for your third meal. You also take their supplements, and two days per week in the first two weeks you drink their cleanse product instead of eating regular meals or drinking meal-replacement shakes. The ingredients of Isagenix include whey protein, fiber, enzymes and herbs, and the Natural Accelerator supplement also contains cayenne, green tea, cinnamon and ginseng, all of which the manufacturer claims assist fat burning. According to the manufacturer, these meal-replacement shakes and supplements improve energy, promote digestive regularity, increase endurance, encourage weight loss and help you maintain lean muscle mass.
Thank you for posting this. I find it deeply disturbing how Isagenix consultants try to tell you how no other food on the planet has as many nutrients. The whey made my skin have terrible and painful acne flareups and the Isagenix Natural Accelerator made me unable to sleep for days. Neither my Isagenix consultant or the company representative I spoke with were honest about their products giving people such side effects. Instead they tried to tell me I had acne before and must be under stress for my job so that’s why I can’t sleep. This is all a pyramid scheme, where they want to make you a lifer while screwing up your digestive system by not giving people the opportunity to let their bodies digest real foods and not processed powder.

I have been reading most of what has been published here … not all because WOW is there a ton of comments … talk about advertising, this could be taken and taught as a Master Class in Marketing … Anyway, I just wanted to make ONE THING PERFECTLY CLEAR and I will be brief and not include links or anything of the like. Anyone who has a Professional Degree, Certification, a Doctor, Scientist etc. CANNOT make false claims … cannot report product ingredients that DONT exist. They simply cannot make reports, claims or put ANYTHING in WRITING that has not been validated or proven by a governing body – ESPECIALLY FOOD; and food that is allowed to be sold to the general public. They will stand to lose their careers, reputation, business, livelihood (and I’m sure most of these professionals do not want to lose their livelihood) … that said, it is profoundly irrelevant if Isagenix Sponsors a study or not … the Doctor or Scientist who puts his/her name to it will be held accountable if their reporting is inaccurate – this is not arguable. And for those of you who will say that they just get paid off to report whatever the Company in questions asks them to do – I’m sure I will also see you rallying at the next UFO pick-up point, or stocking your fallout shelter for the coming “End of Days” ushered forth by the “One World Government.” So, while I like some of the points you make Dani, you cannot deflate and set aside information because it came from the Isagenix website or further, you cannot discredit any information source because it comes from the producer of the product (let me be clear, I am speaking only for the the FOOD WORLD here – not Spiderman toys, or toothbrush makers) – do you really believe that the world, the government, will allow just any LARGE organization to produce whatever FOODS they want, however they want to, without any organized, highly educated Governing Body to be held accountable to? Just to make money? If so, then see you at the rally.


I wrote this Isagenix review because I do not want you to fall for meal replacement shakes, for protein bars, or otherwise gimmicky foods. These companies produce cheap, toxic products and push them off on people as healthy alternatives (to what exactly I’m not sure). Instead, watch my video on how to make a protein shake that is not only unprocessed but actually good for you.
– Dr. Suk Cho – Dr. Cho received his B.S. in Biochemistry at Juniata College, his M.S. in natural product chemistry at Miami University, and his Ph.D. in Organic Chemistry at Emory University. He has more than 30 patents and has authored or co-authored more than a dozen articles or abstracts in peer-reviewed scientific journals. Previously, Dr. Cho served on the Scientific Advisory Board or in upper-level management of R&D for a variety of nutrition-related companies. He was also R&D manager for global consumer product giant Unilever for nearly a decade.
Debate provides a platform informed choice – in the spirit of increased knowledge and insight – thank you for this blog. We are all doing the best we can – for our bodies for our future 🙂 This program works for me – I am not an evangelist – as it may not be for you – but it just might be a better option than what people choose now – with obesity as an epidemic – I would suggest its the mainstream consumption habits of the western world that require a sprinkling of this education contained within this blog.
I cannot thank you enough for ALL of this. You are a hero in my eyes. I have been training my five children how to eat an organic, non-gmo, real, whole food diet (gluten free) and will be sharing this info with them as we are being bombarded at church (yes, church) and school by isagenix sellers. Real food and healthy moderate exercise are the key. xo
Do not use if safety seal is broken. Do not exceed recommended daily intake. Do not use if you are pregnant or nursing. Not intended for use by persons under 18 years of age. KEEP OUT OF REACH OF CHILDREN. This product is not intended to be used without breaks. Cascara sagrada belongs to a family of plants containing compounds with laxative effects. With long-term use without breaks, this ingredient may interfere with diagnostic imaging procedures of the colon. Taking a break of 30 or more days between use cycles will help maintain natural regularity. Not intended for long-term use.,
Here’s where some of the discrepancy lies… these people (and I was one) are spoon fed that the proteins come from grass fed cows and the whey protein is undenaturated, what they are failing to see is that your review questions the low heat non fat dry milk. Both of which can be true, the company may in fact use grass fed cows that produce the whey protein BUT it also adds low heat non fat dry milk 🙂
I actually use Isagenix and I’ve lost 15 lbs so far. I absolutely agree that shakes and supplements are not the way to go. But I also am honest with myself: I work three jobs and have very little time for anything. When it’s time to eat, I’m usually in the car, going to the next job, and end up eating poorly because of it. Doing a shake for two meals helps me so much because I know I’m not going to make a bad food choice (like fast food) and I can also drink it in the car. HOWEVER, I don’t like how expensive Isagenix is. I work three jobs because I’m a musician and while I love what I do, we make next to nothing. I certainly can’t keep doing Isagenix. I can’t afford it. However, from Isagenix I have learned how to choose things that fill me up and are healthy (I’m speaking of the one meal a day here – I have a ton of veggies and usually put quinoa and black beans [I don’t really like meat very much] with it, along with a teensy bit of olive oil) So…
Also, I was extremely frustrated after I initially signed up. The person who had “sold” me on it immediately sent me links on how to branch out and get people to ask me about it. It was suggested that I post my success (there was not success) on my facebook page and to watch videos on how to talk to other people in order to sign up. The exact words were “you will be a great brand rep as you are already active and healthy, people will flock to you”. That was not my intent at all and I did not sell it to one person.

Sorry if I missed this somewhere along in the thread. It was dizzying reading through the comments and I had to skip to the bottom. I can see where it becomes so difficult for people to make good choices or know what to trust with so much different information out there and competing facts about ingredients. I just watched the documentary “Fed Up” this weekend and that also illustrates how people can become so misguided and it’s really sad. From now on, sticking to my gut and trying my best to eat clean, organic real foods!!
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