I recently read about the various P450 enzymes and their role in detoxifying our bodies…Could pesticides and additives have an adverse effect on these enzymes? I would love to see the research, but my instincts after reading more into the subject say perhaps. The question pertaining to this post concerning Isagenix supporting proper detoxification or not isn’t my point. My point is that the “old school” thinking of nutrition in the light of “every calorie is the same” needs to be thrown out. Isagenix at least supports people in making healthier choices…Kale instead of candy perhaps. You are what you eat, and heck, if Isagenix gets people to drink a nutritional shake vs eating a happy meal, I’m all for it.
The “heart healthy” diet is ridiculous – it consists of grains, low-fat foods, minimal meat, and processed food byproducts. It’s the opposite of what people should eat for heart health. Like I said in my other comment, when you’re testing against horrible diets in the first place, it’s not surprising that the outcome is positive. But it doesn’t mean that the products are ideal.
This is the kind of information I was looking for. I found it very strange how few negative reviews were available for Isagenix system. I am from the “school” of where if something seems too good to be true, it is because it IS too good to be true. 400 dollars for a 30 day system sounds to me like a rotten pyramid scheme with a frantic dietary fad.
There is absolutely no Soy protein. They use soy lecithin as an emulsifier…Lecithins are oily substances that are naturally found in plants (soybeans) and animals (egg yolks). It is extracted for use as an emulsifier in many prepackaged foods such as ice cream, milk shakes and chocolates. As an emulsifier, it helps keep fats and water from separating and produces smoothness in our IsaLean Shakes and IsaDelight Plus dark chocolates.
I’m not sure what you mean by “strict paleo” and I’m not sure how long (or short) you were eating this way. Paleo is about eating unprocessed, organic, local and sustainable food that is tailored to your own personal needs. So in short, I honestly do not believe your testimonial, or that you were properly tailoring a healthy diet to your individual needs.
Of course inflammation is a normal response, that’s kind of obvious. But you should know that with modern-day diets, stress and sleep, inflammation is rampant. You should also know that due to modern day diet, omega-6 is ubiquitous; in fact people eat way too much omega-6, which leads to inflammation. Inflammation is the basis of all disease. Vegetable oils are extremely high in omega-6, which makes them inflammatory. Which was my original point because these products contain vegetable oils like canola, fractionated palm kernel and sunflower, which are all inflammatory.
Juice diets do prevent your body from going into a state called ketosis, he says. Ketosis means your body has no carbohydrates to burn for energy, so it has to burn stored fat or whatever else is available, he tells WebMD. "You feel bad, even smell bad. That's what makes you feel like hell during a [water-only] fast. But is that because the toxins are coming out? No! You're going into ketosis. It's known physiology."
I just wanted to thank you for your review of Isagenix. I have been doing some research because some close friends have been pushing this product on me. However, with both parents as personal trainers and a history of being in top shape, I know that this is not the right choice. I’m too nice to let my friends down without some real facts to back up my reasons why and your review gave me a lot to work with!
Now am I necessarily recommending it, no. As I do believe it to be not a once size fits all type of solution to the obesity epidemic. But for one who understands their underlying weigh loss issues and is under the care of a physician, this program may help jump start your weigh loss journey. The program does however require will power, it won’t be easy. I did however find it comforting that program was only 9 days.

The Code of Federal Regulations defines a natural flavor as “the essential oil, oleoresin, essence or extractive, protein hydrolysate, distillate, or any product of roasting, heating or enzymolysis, which contains the flavoring constituents derived from a spice, fruit or fruit juice, vegetable or vegetable juice, edible yeast, herb, bark, bud, root, leaf or similar plant material, meat, seafood, poultry, eggs, dairy products, or fermentation products thereof, whose significant function in food is flavoring rather than nutritional (1).” Artificial flavors are defined as those that do not meet these particular standards.
If you want to lose weight, eat less than you burn, full stop. Learn to cook and eat stuff you make yourself. Don’t waste your money on organic either, as if anything the anti-GMO movement is even scammier than Isagenix. Teach yourself enough biology and chemistry to understand why these are scams. And most of all, accept that successful weight loss takes time. It’s a long-term project; don’t rush it, or buy into shortcuts.

The particular products I use are all gluten free and it is keeping me healthy. I had all kinds of aches and pains before I started drinking Isagenix shakes and my cholesterol was a little high. I just went for my annual doctors visit and I have never been healthier. My blood work all came back perfect and my cholesterol is lower than its ever been, and my good cholesterol is in a great place. Again, I’m not saying you’re right or wrong or that I’m right or wrong. I just want you to not be so closed minded. There are very healthy aspect and not so healthy aspects about all plans, which is why different plans and approaches work for different people and their particular needs. I’m not bashing your way and I’m just asking you not to bash mine. Any good professional will be able to argue both sides of any story. You have to be flexible in life. That’s how you learn new things and grow.
The comment on ‘natural flavors’ is misleading as, to start, there is no MSG in the shakes even though you say technically it can be classed as a natural flavour. Actually it can’t as USDA will not allow MSG on the ‘natural flavors’ list. It does, on the other hand, allow glutamic acid. Glutamic acid is an amino acid that occurs naturally in our bodies. Aside from this, you do not actually know which ‘natural flavors’ are in the product. Before making suggestions of what they might be and misleading people, actual research could involve you asking company, if you were genuinely doing an ‘unbiased’ review on the internet for literally everyone to read.
– Dr. Suk Cho – Dr. Cho received his B.S. in Biochemistry at Juniata College, his M.S. in natural product chemistry at Miami University, and his Ph.D. in Organic Chemistry at Emory University. He has more than 30 patents and has authored or co-authored more than a dozen articles or abstracts in peer-reviewed scientific journals. Previously, Dr. Cho served on the Scientific Advisory Board or in upper-level management of R&D for a variety of nutrition-related companies. He was also R&D manager for global consumer product giant Unilever for nearly a decade.

This now raises another question………….. how many of you Isagenix supporters have signed others up to this program? I bet there are a few. Now, my next question is….. how many of you have enough medical knowledge to stand over what you are advising people to take? Remeber, you are now responsible for whatever happens to someone as a result of them taking the product you pushed. If they have certain allergies or ailments, some of these products CAN cause health problems in certain people.
I just have to say since I can not post the pictures I took of the IsaLean Shake container the issue can not put to rest. There are no DENATURED protein in Isagenix IsaLean Shake and is FREE of GLUTEN and SOY (reads on the front of the container). I take it and I looked the actual ingredients and all I read UNDENATURED and have not found anything that reads “artificial” There is FRUCTOSE, but I as looked up fructose I found this article: http://lowcarbdiets.about.com/od/nutrition/a/fructosedangers.htm
Hi Dani, I absolutely love your article. You are extremely knowledgeable. I hate everything to do with GMOs and Monsanto. I avoid processed and non organic foods and only buy local organic foods. I am a health and fitness coach and I try to steer my clients towards organic products. Recently I have been asked about this product and I knew very little on it. The only thing I knew was they claimed to be “Non GMO and Organic” I now know they are not. Isn’t it a shame that we have to worry about what is in our food? I am so glad I stumbled upon your article!! Best wishes!!
I found myself about 25 days ago, being faced with the choice of trying Isagenix. I looked into it. I did some research. I was discerning. And given that those who introduced me to it were close family and I had been watching their results closely and was actually impressed, I decided to give it a go. But lets be clear about something: I owned that decision completely. It was not sold, because I will not be sold to. Now, 20 days in, so many of my hopes and dreams are back in gear and the adventures I’ve been hoping and praying to be part of are within my conscious control. Isagenix didn’t do that. I did. I saw Isagenix as a tool and I realised that my application of that tool would be paramount to the success or failure of the venture. Sure, I understand and appreciate that some of the ingredients are suspect. But so is the fluoride added to water supplies that is still mandatory in most provinces and states of New Zealand and Australia where I’ve spent the majority of my 39 years. And we know what that stuff does to our pineal gland… right? And what the pineal gland does for us and how important latest neurological studies are suggesting it is to our overall experience as “living systems?” I really hope thats a bandwagon those of you with “credentials” are on. I don’t mean that disrespectfully, I sincerely mean that.

One of my children takes lessons from a business pushing Isagenix as a way to increase fitness. I’m going to have to respond directly and if they push back, I’ll just provide the URL to this webpage. MLMs have always been around and will continue as long as we allow them. Kind of like cults are the price we pay for religious freedom. I think the more savvy MLMs are figuring out to jump to the next thing (as in the MD who started Isagenix) before serious analysis and critiques come out. But thanks to the Internet and angels (thank you Sequence Inc. and contributors) who will keep outing them, these snake oil salesmen will have to be faster than ever at duping unsuspecting clients. The simple fact is that “if it sounds to good to be true, it is.” And there will never be a replacement for the simple mantra from “In Defense of Food. Eat food. Mostly plants. Not too much. “
Soy protein is not in any of their products. Purified soy lecithin is in some of their products including the Black Sesame shake (but not the french vanilla or dutch chocolate or berry harvest shakes). However the lecithin is not the same as the protein as the author would know. It’s the protein that is the hormone disrupter. More details on why isagenix uses soy lecithin is found on their site http://www.isagenixhealth.net/why-is-soy-lecithin-used-in-isagenix-products/
Instead of using Isagenix products whether it is for weight loss or for muscle gain or energy & performance, what would you recommend to be a healthier option or diet to begin with, just say to feel more energised? I myself have gone to incredible lengths to gain more energy and still haven’t been able to find an answer. Whether its changing what foods i eat (carbs/fats) or keeping hydrated by drinking up to 1 gallon (3.785ltr) of high alkalised (9.5PH to be exact) water per day or getting more sleep. I am a pro. footballer from Australia and still being quite young, my aim and dream to play overseas has never been higher. I came across your blog as i am just about to get started on Isagenix and i wanted to add a little more research to gain a better understanding about the product because to be quite honest, i am unsure as to how all of their products will effect my body/health. I have spoken with plenty of health professionals about what foods i should be eating, when i should eat them, all the where’s and how’s and to be honest, I’m sick of wasting my time/money going around in circles not finding any results. I have also done a bit of research by myself (not a lot or else i would probably be as qualified as you are haha) and still no luck. How can i find what will work and be beneficial for me, with out “trialling” products for 30 days and “hoping” it will be right? To put it straight, i am sick of this trial and error BS and honestly would love to know something, anything that will help assist my performance playing football and feeling more energised. If there is any chance you are able to provide any websites that I can take a look at, that would be incredibly helpful not only to myself, but to everyone reading through your blog as it would give a number of different, healthier alternatives but very similar results.
You speak specifically about Calcium D Pantothenate. This is also referred to as vitamin B-5 or pantothenic acid, is an essential nutrient your body uses to generate energy by breaking down carbohydrates and fats. Adults should consume at least 5 mg of calcium D-pantothenate each day to maintain a healthy body, according to the University of Maryland Medical Center. If you have trouble getting enough of this B-5 vitamin from your diet, your doctor may recommend treatment with a calcium D-pantothenate supplement.
I give the shakes to my kids and of course they also eat plenty of real food. My daughter who has always been small and had asthma and chest colds has stopped getting sick and shot up in the last few months. We were eating an organic, whole food diet before we started Isagenix. I took a very long time to sign on because of the fact that it IS a network marketing company and I am very well-versed in nutrition and supplementation. (Incidentally, I think it is INSANE to think that you can live in this toxic world and be able to effectively detox and fill your nutritional needs without SOME sort of vitamin or mineral supplementation, whether it be through soaking in salts or imbibing) We were using ALL of the holistic tricks and we were still getting sick on a regular basis. Since being on isagenix I have noticed that it has fixed a long-time hormonal balance that I was suffering from–which was making my periods really rough. I also feel as if sickness cannot get a hold in my body. In addition to that, I have had all of the other benefits you would expect taking high-quality supplements. I am happier, sleeping better, have more energy etc. In the interest of full-disclosure, I am “selling” the product. I have helped a number of people get better from-long term illness as well as lose weight with this line.
I was recently sent this article/blog/discussion by a patient. I get hundreds of “Dr. Google” articles sent to me to evaluate and frankly, I evaluate products and supplement/diet systems for a living from a physician’s and nutrition and medicine perspective. Old companies (GNC, Vitamin Shoppe/ Hebalife/Shaklee/4Life/Usana/Nuskin, etc) and new companies/products (IDLife/SilverWolf, etc) and all the “new and improved products” each produce. They all have commonalities: Most products are not new, just recombined and renamed. No one can distinguish the sourcing of ingredients just by reading the label, and it is very difficult for the consumer, let alone the self described online blogger experts to distinguish and evaluate the science and science officers of each company and product.
An Isagenix-funded study published in Nutrition & Metabolism in 2012 found that over an eight-week period, people who used Isagenix meal-replacement shakes as part of an intermittent fasting and calorie-restriction diet lost 2.2 pounds more than those who followed a similar diet using regular food. However, according to a 2012 article published on the Science-Based Medicine website, this study wasn't well-designed, and Isagenix paid to get it published in the journal. The author of the website article, Dr. Harriet Hall, also noted that there were inconsistencies in the numbers listed in the results, potentially making the conclusions unreliable.
We all know that most meats are produced with additives that makes the animal grow and mature faster. These additives have been declared safe by all who tested them. Most of us have seen a young girl who looks like she’s 18 but is only 12 or 13. It would be logical to assume that the additives used to grow the animals faster would have similar effects on the people who consume them. After all, humans are just animals too. Did the scientific papers covering the use of these additives fully test and research the affects they would have on people? One could argue that it’s not a bad thing for our kids to grow faster but is it a good thing?

I too was encouraged to try that Isagenix product. 1 of my siblings is heavily into the scheme. She suggested it to me, and I tried it for almost 5 days until I started experiencing negative side affects. A week later she asked me if I wanted go with her to an Isagenix event where I’d become an associate., but after I naive agreed she informed me at the last minute that she needed to submit my social security number to the reps in charge so they could make an isagenix account for me, and for their tax purposes too. She had everything planned for the trip. But I felt pressured/trapped about giving out my ss number. I also did research about the product and I was shocked when I found it was a scam. It makes no sense why suddenly the company wants my ss number and insists I buy another of their products just to be a seller. So I politely informed my sibling that I refused to just throw out my personal info when I knew the company wasn’t Real!

Every time you eat, your body digests the foods you consume, then absorbs and transports nutrients to all of your body’s cells through the blood stream. Your cells can either use these nutrients right away or store them for later. When you consume more food than your body needs at any one time, it can lead to a back-up of excess nutrients for your metabolism to manage.
This easy a.m. ritual works on two levels. First, a recent study found that exposure to UV rays, even on a cloudy day, between the hours of 8 am and noon reduces your risk of weight gain regardless of activity level, caloric intake, or age. Researchers speculate that the morning light synchronizes your metabolism and undercuts your fat genes. And burning calories before you eat means you’re exercising in a fasted state—the energy you burn comes right from your fat stores instead of the glucose still in your system. According to some studies, exercising in a fasted state can burn almost 20 percent more fat compared to exercising with fuel in the tank.
So, Dani, your world appears to be about being fit and healthy. You take a holistic approach to that. You advocate organic food – and that’s fine as long as we recognise that this food is subject to the toxins in the environment – like fumes for example on their way to market just as we are on our way to buy them. Does the organic farmer check the trucks they use to ensure the fumes from the vehicle itself isn’t polluting the carefully grown crops in organically optimised soil?
Im away from home for 13 hours a day with work (on an island which I have to catch a ferry to and from), I have a dog who deserves some of my time daily, like to keep a clean house, have clean clothes every day, get some exercise daily if I can, and I don’t have a wife to cook for me like most of my work mates do. So far with the cleanse, I initially dropped 4kg and 3 belt sizes, (1st time under 110kg in 10 years), am sleeping better, given up coffee, thinking clearer, no more inflammation in my joints, and I now have the energy to: work out more often (I’ve put 1kg of lean muscle back on bringing weight loss back down to 3kg), give my dog more exercise, and most importantly, I now have the energy and the drive to plan my main meal for the day with the absolute focus on the very REAL and natural nutrition you imply from organic produce. I’ve known about good nutrition at least at a basic to intermediate level for some time because I care about my health and I realise that only I am the authority with which my life and health depend. Intimately. But that doesn’t mean that I am immune from the pressures of life, long hours at work, bills to pay, adventures to plan and pay for, etc. I am human. And so we all are. All so very different in our experiences and subsequent characters, yet so very much the same in our inherent nature.
Ancestral Nutrition Robbie Bianchi Pray I didn’t even address the “natural flavors” in my post, which in hindsight I should have because it’s just another reason these products are not healthy. To each their own, it’s entirely up to you what you put in your body. Personally, I choose to avoid toxins and most likely GMOs, especially because I don’t want to support Monsanto. Also just as an FYI – it’s not legit to retrieve accurate, unbiased information from a website whose intention is to sell the very product you’re researching.
Of course inflammation is a normal response, that’s kind of obvious. But you should know that with modern-day diets, stress and sleep, inflammation is rampant. You should also know that due to modern day diet, omega-6 is ubiquitous; in fact people eat way too much omega-6, which leads to inflammation. Inflammation is the basis of all disease. Vegetable oils are extremely high in omega-6, which makes them inflammatory. Which was my original point because these products contain vegetable oils like canola, fractionated palm kernel and sunflower, which are all inflammatory.

I don’t even know why I’m responding to this as opposed to trashing this comment. It’s evident that you know nothing about nutrition – you just said soybean oil is high in omega-3s. Uh no, it’s high in omega-6 which causes inflammation and heart disease. This is literally a fact. Not to mention the fact that soy oil is extracted used hexane – a neurotoxin. I’ve provided several credible links about soy oil. Please look for them in the comments section, it’s incredibly frustrating to repeat myself almost daily to people who don’t have the slightest grasp on nutrition. And unlike you, my sources are from sources that are actually credible – i.e. PubMed.


I have started isagenix and now at day 8 of a 30 day cleanse. I am doing to give it a try as a my personal trainer mentioned it to me. I can only concur with Dani about the ingredients list as I have all the products she has mentioned which are the ones you mention Megan too and they have the ingredients that Dani has published on her blog. THEREFORE isagenix does is gluten, contains fructose, maltodextrin etc. So someone really needs to read the back of the packaging! As I said I am giving it a go as a template to regulate eating habits and to see what are the benefits as was looking for more energy. Australian farmers are the most efficient producers of food we need to eat everyday. Lets just buy fresh food and then we would all be a lot healthier!
Not true Riley…Most people associated with Isagenix share it because they feel awesome and their lives have been changed. Not all…most. I share it because it has truly changed my life. I am an RN and I would encourage you to do your due diligence and study the facts and ingredients and how they are processed. John Anderson is a genius. He extracts the nutrients from food sources. They are not chemical based. But as you know from chemistry even nutrients from food sources have chemical names…remember organic chemistry? The whey protein used is undenatured and 99% lactose free. That is a fact.

In regard to high oleic oils, I came across this in other countries’ Isagenix product content (by selecting a different country at the top of their website). The label does state in Australia, Canada and Malaysia and Taiwan (for example, on the IsaLean bars and the FiberSnacks) that it contains high oleic sunflower oil. As far as I am aware, the products distributed world wide are made from the same ingredients in the same place. So there seems to be a difference in labelling requirements in the USA. Incidentally, I am not from the USA.

Herbalife, Isagenix… and all the rest. Those products are all terrible and marketed disingenuously, taking advantage of people’s ignorance on nutritional matters. However, this article is truly awful and just presents a different set of bad information also sourced from people profiting from people’s ignorance on nutritional matters. Mercola, specifically.


I am done here, comments always seem to go one sided, since this article belongs to Dani, so its obvious. I can only say from my personnel experience that isagenix helped me. The same ground beef that Dani is promoting as safe is what got me get cancer in my thyroid. Entire thyroid was removed and no matter how healthy I eat, my immune system was weak and cause all kind of health issues, until I discover Isagenix. It boost my immune system, give me lots of energy, my allergies and joint pain are gone and I have never felt so healthy in years. I lost all the weight I gained since my surgery. Everybody has something that works for them and for me it is what it is. Do not deny that from me, because I am living proof it and loving everyday now. If I get my health back due to organic healthy eating alone, I would make the same comment, but the truth is it did not help me.
The cleansers in my Isagenix Facebook group said it would be easier after day five, and they were right. I got used to drinking a shake for breakfast and a shake for dinner, and looked forward to my low-glycemic lunches like it was Christmas morning. (I was salivating as I put pieces of lettuce into a container at the salad bar.) Though I didn’t lose any more pounds than the previous weigh-in, this didn’t deter my motivation. For the first time in a long time, I’m feeling good—digesting food nicely (in the past, I’d have a bit of a rumble here and there), and oddly, I have more energy than ever before.
The only thing you should be embarrassed about is that you’re a health coach manipulating people into buying an inferior product so you can profit off of them. It’s not me who doesn’t represent “our profession” well. We do two very different things. I coach people to become healthy via an unprocessed diet, whole foods and an overall healthy lifestyle; not relying on a quick fix, meal replacement product that causes people serious health issues.
Hey not everyone has the ability to exercise (possibly due to any injury). So for some of us Isagenix has been a life-saver. It’s not just about the weight loss. I have never felt better in my life! And by the way, I don’t sell it, I use it for my own personal consumption. And it is gluten free!! I’m sorry everyone is entitled to their own opinion, but that’s just what it is “opinion.” Not everything is going to work for everyone, but that’s what makes the world go round! People need to make their own decisions based on their own personal needs. For me, Isagenix in conjunction with super clean eating has been the answer.
Cleansing to ‘kick-start’ weight loss is like getting a base tan before your holiday to Mexico. It’s a useless waste of time. In the end, the weight you lose from extreme dieting and cleansing is mostly water, which will return as soon as you resume eating a normal diet.  It’s just basic physiology. I know the promise of ‘transformation’ in just 30 days is tempting, but it’s also close to impossible. Again, please don’t let emotion dictate your choices here.
I’m not sure what you mean by “strict paleo” and I’m not sure how long (or short) you were eating this way. Paleo is about eating unprocessed, organic, local and sustainable food that is tailored to your own personal needs. So in short, I honestly do not believe your testimonial, or that you were properly tailoring a healthy diet to your individual needs.
I also stated: They repeat the tired old myth that our food isn’t as nutritious as in the “good old days.” They put digestive enzymes in their products to help you assimilate them, not realizing that orally ingested digestive enzymes are themselves digested in the stomach before they can do anything. They say that their electrolytes “ignite the body’s electrical system” – I have no idea what this means, and it certainly is not scientific terminology. – Again none of them could comment.
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