Hi! Very interesting blog post and comments section. I was given Isagenix by my sister and am currently on Day 4 of a 2 week “cleanse”. Prior to her giving it to me, I told her that I was wary of the product because I could not find any research supporting Isagenix that was not influenced or purchased by the company itself. That’s odd, especially for such a large company with so many supporters and testimonies. Despite my hesitation, I agreed to try it. I am obese and have been having trouble with sleep apnea, shortness of breath, and heart palpitations. My typical weekly diet included regular doses of fast food, pizza and at least 2 liters of fit soda per day. Frankly, I believe that Isagenix DOES contain things that are unhealthy. However, it is likely that they are less unhealthy than the disgusting things I was already consuming everyday. My plan is not to use Isagenix for life. I can see why people do, though. It’s a matter of convenience (and for some, a matter of pride). I am using this period to move from being completely unhealthy to embracing real foods again. There’s something about two shakes a day and a 48 hour no-solid-food period that just makes you appreciate something simple and natural like a sweet potato. (Please please please don’t tell me sweet potatoes are bad for me. I just fell in love with them.) I fully intend to return to a life of real food, which I believe does have everything we need to be healthy and thrive. I just needed a way to “reset”, to start the change I know my life needs.
I appreciate the information you have brought to the forefront. I have been a practicing healthcare provider for over 14 years now. I have used high quality supplements throughout my career in efforts to help people become more healthy. I have the ability to see health from the inside using objective data. We use blood, urine and other clinical testing to assess sickness and toxicity. I am someone that does their due diligence in order to put my name on that recommendation for my patients. This is precisely the reason I use the highest quality supplements from high quality companies, this one included. If I feel one company uses a superior product, I will use that particular supplement for that goal. I have always said I would not be married to any one company and feel that I have some of the best companies at my disposal for my patients. With regards to the deep cellular / molecular cleanse I have not seen anything work nearly as well as Isagenix, using objective data.
The Clean Program is simple. Rooted in Functional Medicine and designed by an MD, this easy-to-follow whole food and healthy cleanse program provides results. We believe you already hold the keys to your health, and we want to help you unlock the door. In just 21 days of nutritional cleansing you can see real transformation and set healthy habits and eating patterns for life.

Proponents say a juice cleanse can purify your body, remove toxins, and kick-start your weight-loss efforts, but many health professionals say that’s nonsense. “Cleanses can be helpful or harmful, depending on the type of cleanse and how aggressive it is,” says Gregory L. Jantz, PhD, a mental health expert and certified eating disorder specialist. “Done properly, they are an excellent way to improve focus, energy, and mood.” Jantz adds that a healthy cleanse involves getting plenty of nutrients through fruit and vegetable juice, not depriving your body of calories by fasting.

I too agree with all that you have said. I have trialled both Herbalife and Isagenix for my own research as I am in the fitness industry. I have gotten more success from telling people to eat a balanced diet of whole foods and the occasional supplemental vitamins (relevant to the goal e.g.. weight loss or muscle gain etc). Whats even worse now is that Personal Trainers are the target to further promote it as the age old saying that ‘my trainer said it was what i should eat’. Shame shame shame to those trainers that do this. They do this to also get more financial benefits from the products as we all low with this multi-level marketing (pyramid scheme).
I’d be more inclined to use Isagenix if ANYONE could even respond to your question about the toxic ingredients. I addressed one person about it and their response, for example, was that Agave nectar is a healthy ingredient. That just tells me that they’ve also been “sold” into the Isagenix sales pitch without doing their own research, and I find that very disheartening.
Dani, you like in your references above to Sunflower oil which is high in omega 6 fatty acids. Isagenix uses “high-oleic sunflower oil” along with cold processed olive oil and alpha-linolenic acid from flax seeds as the main sources of fats. Consumptions of which has been linked with better control of blood pressure and heart health. More details at:
Thank you for posting this information. I have been on quite a journey the past two years making many changes to my diet. The biggest change is eating a paleo lifestyle. I stopped eating most of the food offered through isagenix because I do believe it is too processed but I have still been consuming the shakes because I find it difficult to eat the amount of protein I need to eat everyday without supplementing somehow. I am an avid crossfit participant and would like to build some more lean muscle. In order to do this I need to eat at least 1g per lb of bodyweight, in my case, 160g of protein. I just ordered the protein you recommended above to give it a try. I am just starting a program to get my masters in human nutrtion and functional medicine. I am sure I will come across information about the ingredients you listed as I move through the program. It is a shame there is not better labeling requirements so people can really understand what they are getting. I truly believed Isagenix was organic, sourced from new zealand gras fed cows without artificial ingredients or preservatives, although I often wondered how it could have such a long shelf life without preservatives! My internal alarm bells have been ringing which led me to do a search that landed me at your post. So here I sit feeling overwhelmed and I feel sad because as educated as I am still believed what the company told us. I wanted you to know your blog has reached a current Isagenix user in a positive way. I started with Isagenix because of the science of what they tell us is behind their products. It is because of this science I got an appetite to know more and that led me to complete my health coaching training through IIN and now enter a masters program to further my studies. For that, I will be grateful to Isagenix. I believe the science they tell us is solid, but it appears their products do not fulfill the requirements to achieve the results the science warrants.
Insulin sensitivity—how well insulin does its job of ushering glucose in the blood (after eating food) into the appropriate body tissues where it is used for energy—also looks to be “reset” by fasting. One study showed that healthy men who fasted for 20 hours every other day for 15 days had increased rates of glucose uptake, signifying improved insulin sensitivity and better blood sugar control (4).
Regardless of the drink or recipe you use, just be sure to stick to unprocessed ingredients. The best detox for weight loss will always require nothing more than what’s found abundantly in nature. The same holds true if you decide to use a detox supplement like Digestive Refresh. These detox drinks alone won’t give you six-pack abs, but they’ll certainly help you achieve your ideal body weight.
Sorry if I missed this somewhere along in the thread. It was dizzying reading through the comments and I had to skip to the bottom. I can see where it becomes so difficult for people to make good choices or know what to trust with so much different information out there and competing facts about ingredients. I just watched the documentary “Fed Up” this weekend and that also illustrates how people can become so misguided and it’s really sad. From now on, sticking to my gut and trying my best to eat clean, organic real foods!!
The only truly effective and comprehensive type of detox is a cellular detox also known as cellular cleansing. Cellular cleansing is designed to remove harmful toxins from the body where they are causing the problem: at the cellular level. While many people focus on eliminating toxic food, which is important, but there are many other toxins that people encounter that are not food related. A cellular detox doesn’t just focus on removing toxic food; it looks at all the potential toxins a person encounters on a daily basis and aims to remove them as much as possible from the body and environment. Before a person begins a cellular detox, it’s important to know what the potential toxins are and where they originate.
But your reason for wanting to do a cleanse may be totally admirable. For instance, perhaps you want to break out of eating patterns that leave you feeling sluggish halfway through your workday, or maybe you'd like to turn down your meat consumption a tad for the environment's sake. In those cases, you can still do what Larson calls a "reboot" rather than a cleanse to accomplish those goals without depriving your body of necessary nutrients.

Ok. Glad we cleared that up. However, I consume both equally and it’s not about choosing one over the other honestly. That is not what I was suggesting. I still love my veggies and fruits and meats and lentils. But yes, I am more confident in the quality, and purity and nutritional value in the Isagenix products because of the extensive testing and research that’s done. Isagenix’s vision is to impact world health. You and Isagenix are essentially on the same team really. Please bring your concerns directly to the company as you were not satisfied with any answers here. I was thankful for this blog as I learned so much. Cheers to great health!
I’m a little late to the party but I tried Isagenix about 5 years ago (before I became a Health Coach). I thought it was an over-priced program and pretty awful, especially the cleanse days with the little wafers (don’t know if they still do that). It’s basically over-priced Slim-fast. I’m absolutely stunned at how many “health coaches” there are out there that sell this stuff. There are a lot of good products on the market and I’m not anti-MLM but the person who sold me this stuff now markets for a company called Qivana and their shakes don’t look any better. Thanks for taking the time to write this!
I like to believe the “thinking” person prefers to make informed choices and decisions about what they put into their bodies, or not. So, I can’t comment on the reasons for the choices people make though I do question the validity and reliability of those reasons from a researcher’s perspective. I can share why I found Isagenix appealing (quick easy fix) and equally unappealing. I’m an early adopter of many things, however, when no (proven) independent clinical studies exist to support something, I tend to smell a rat. I know there is anecdotal evidence and millions of photos to support Isagenix. That’s called the perfect marketing strategy. 

What I DO care about is the use of the word “unbiased” in your title. Just because you use facts does not make an opinion “unbiased.” Facts can easily be twisted to suit your needs, see the above paragraph about fructose…. So you don’t eat fruit, ever, right? Because of the horrid fructose? Or do you eat some, in reasonable doses? My guess is the latter. How horrible for all of those people who died from eating too much fruit. Except that you said you recommend honey as a viable sugar alternative, and honey contains fructose. You shouldn’t eat honey, it contains fructose and fructose is toxic.
I will not become hostage to a company, any company. If I have to pay for supplements, shakes, wafers, etc., I am not learning how to eat properly – someone else is doing my thinking for me. No doubt I can lose weight with Isagenix, Jenny Craig, Nutrisystem (“Lose up to 10 lbs. in the first month or your money back” which means if you’ve only lost one pound, they’ve still met their obligation). Give me the Mediterranean Diet any day.
Tracy, why aren’t you calling out the real scams like vaccines, GMOS, chemo, etc that the rest of the world isn’t buying into? If science is so great why is autism, chronic disease, cancer on the rise? Oh that’s right… How would you get paid? You really think you are fooling anyone? You are just a shill, in your terms, for the real scams… The difference with Isagenix is if I don’t like it I can stop, I don’t have a choice to eliminate the attack on me when my water is fluoridated, or there is GMO’s in that supposed organic food or there are pesticides engineered into the food that doesn’t wash off… Your lack of common sense is stunning… It is next to impossible to eat healthy in America even if you wash your produce you moron!
What people fail to realize is that for at least the past 60 years, corporations have taken over our food, our farming, our medical field. Basically, our life. THEY dictate what we should eat, what we should feel, what we should wear, what we should buy, basically, how we should live our lives. It’s called consumerism, and consumerism means dollars, which help keep the corporate board members happy and insanely rich.
For me this is hugely off putting, and totally disgusting. I am not someone who just follows blindly, I did my research into in for almost a year and was very hesitant to try it, I spoke to alot of people read alot of articles, and also did as much ingredient research as possible, but the whole thing seems so filtered, that only certain things get through, as long as they approve.

I like this article. I think it is always good to have multiple opinions about a product. It’s like a good cup of coffee, best when well-rounded. I’m currently using Isagenix. I had initially purchased the 30 day cleanse, having been sold on the idea. But after two days of the shake days I was dead to the world and knew I wouldn’t last through the 48 hour cleanse period. They even sent me home early from work on the second day because I was so out of it. I have no doubt that part of this was due to the fact that I workout for 12+ hours a week and I’m 5′ 11” so the calorie intake was far too low for me. An oversight both on my behalf and my sponsor’s. I quickly decided that maintaining my workout schedule was far more important to me than completing the 30 day cleanse so I decided to take the cleansing a little bit slower thus deviating from their suggested schedule. I just take the cleansing powder in the mornings after the Ionix Supreme, take one shake in the morning, the other either before bed or at work along with the accelerator at the appropriate times while maintaining a calorie deficit that I am comfortable with. I’ve noticed a few things:

Anyway, I saw someone that I knew was saying they had good results and had lost a lot of weight in a short amount of time, so I wanted to know what they were using. That person connected me with their rep/coach who sent me a link to watch a video, and the rep gave me a call (sorry I am using all kind of incorrect pronouns – just trying to respect their anonymity). The rep mentioned a food package and I immediately thought about nutri-system with the prepackaged meals, but I learned that basically the food is supplements, bars, wafers, etc.


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undenatured whey protein, olive oil, flax seeds, medium chain triglycerides (from coconuts), cinnamon, digestive enzymes, alfalfa leaf, sea salt, pysllium seed, vitamin C, iron, iodine (from kelp), stevia, zinc, wild yam, prebiotics and pro biotics, calcium, vitamin B12, folic acid. You are getting 8 grams of fibre per serving, 24 grams of protein, only 11 grams of natural sugars, no gluten, no soy protein, 21 vitamins and minerals, low glycemic, amazing amino acid profile etc etc. This is their isalean shake their most popular product.
I agree that all natural is the best way to go. Recently came across the Wahl’s Protocol reinforcing my belief. Have also reviewed studies and TV clips, including 60 Minutes coverage, about how any type of sugar is in fact toxic and increases the bad kind of LDL is our bloodstreams leading to more heart disease. Any company making money by selling a weight loss diet to and because we are a mostly uneducated public, while not illegal, is borderline unethical and most likely quite profitable at least for those who own the company or are high up in the ranks. The list of product ingredients provided above looks to be low quality/least cost similar to highly processed food items. This may lead to an increasing likelihood of negative health side effects as time goes on.
Far from being a “toxic sludge” as suggested around the internet, the phospholipid is an important part of all cell membranes. It plays a role as a component of bile in the small intestine and is a major source of choline in the diet, which is vital for proper metabolism of fats in the liver. It’s also a precursor for acetylcholine, a neurotransmitter in the brain. For these reasons, you may see lecithin available as a supplement in natural health stores.
The bulk of the food items on the list consists of green leafy vegetables, lean proteins and healthy fats. The trick is to follow it to the T. So if you find yourself wondering whether you can eat something that’s not on the list, the answer is no, you can’t. It’s a simple rule that’s not easy to follow, but bear with it for just a week (and perhaps review my clients’ results – they all stuck to it).
It was as if no one had actually read what I wrote. No one bothered to address any of my specific criticisms. No one even tried to defend Isagenix's false claims that toxicity accounts for most disease, that the body protects itself from toxins by coating them with fat, and that internal organs become clogged and deteriorate if you don't cleanse. No one offered any evidence that “detoxification” improves human health. No one tried to identify any of the alleged toxins or show that they are actually removed. No one tried to provide any rationale for the particular combination of ingredients (all 242 of them!) in Isagenix products. No one questioned my assertion that “no caffeine added” is inaccurate labeling because green tea, which is added, contains caffeine. No one commented when I observed that the amount of vitamin A in these products is dangerous and goes against the recommendations of the Medical Letter. No one offered any evidence that more weight is lost by adding Isagenix to a low-calorie diet and exercise. I offered some alternative explanations that might account for people believing that Isagenix is effective when it isn't; no one commented on that.
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