Oh no, it’s the same old ‘fat burning’ claim. Natural Accelerator throws all of the usual suspects together for the typical ‘metabolism raising’ supplement: cocoa, green tea, apple cider vinegar, cayenne, cinnamon, chromium, and of course, ionic alfalfa! Isagenix seems to be quite fond of ionic alfalfa, even though it has basically zero evidence behind it. Maybe the ‘ionic’ part makes it sound all science-y and effective, even though it probably isn’t. 

love the infoLove the info you post on here. Keep up the good work. I agree with you totally and people should fully read what you put down before getting on their high horse and telling you your wrong which you are not. Also on a side note you are very beautiful and I love what you stand for. Keep up the good fight. Education is the only way we can get our country to change its bad eating habits. If it didn’t grow naturally from the ground it should be left alone. Be smart about what you put in your body and the portions that you’re putting on your plates. Fad diets like all the shake programs out there will always leave you looking for the next quick program and you will have wasted hundreds of dollars and put the pounds right back on when you get board or no longer can justify the outrageous cost of which ever get thin quick program you are on. If you want real nutrition, stop with all the pills and supplements. And quit eating in front of your TVs. Cook a meal, get educated and stop blaming everything.


Well said. I have used Isagenix in the past and it is good for a quick weight loss because you cut calories, cleanse days you eat nothing, so yes you lose weight. But it all comes back. I am now finally learning about proper nutrition and exercise, especially cutting sodium and keeping stress levels down. My next move now is to take up yoga which I heard has great stress relieving benefits.
Proponents say a juice cleanse can purify your body, remove toxins, and kick-start your weight-loss efforts, but many health professionals say that’s nonsense. “Cleanses can be helpful or harmful, depending on the type of cleanse and how aggressive it is,” says Gregory L. Jantz, PhD, a mental health expert and certified eating disorder specialist. “Done properly, they are an excellent way to improve focus, energy, and mood.” Jantz adds that a healthy cleanse involves getting plenty of nutrients through fruit and vegetable juice, not depriving your body of calories by fasting.
I think sometimes people in your profession forget just how much most regular people do not know, and condemn products that may be a far better choice when compared to what they are currently eating, as in my case. What that does, is confuse people even more and they throw up their hands in defeat and return to their good old American Processed diet. An entire generation plus, has been born and raised into this over processed, convenience food country….Perhaps the all or nothing approach to better nutrition with them will not work? It does appear to be failing, as American’s keep getting heavier and heavier, and far less healthy than say 45 years ago. But wait, not true, we have pharmaceuticals to keep us alive in our unhealthy state even longer 🙂

Most of the shakes contain around 11 grams of sugar. If we assume half of that is fructose and people are consuming two shakes a day, plus one of the snack bars, like this one: http://www.isagenix.com/~/media/product/isalean-bar/isalean-bar-fact-panels/us-en-fact-panel-isalean-bar-chocolate-decadence.pdf which contains fructose and a whopping 16 grams of sugar – a person would be consuming at a minimum 20 grams of fructose per day – not even including any they’re consuming from actual food! And it’s worth mentioning that PaleoLeap is including naturally occurring fructose, ya know, from an unprocessed, whole food. Not from an overly processed shake or “IsaLean bar.” For someone who likely already has issues with blood sugar, insulin, liver function, etc – they should be consuming nowhere near this much fructose.


Not sure if you are familiar with online marketing, but looking at all the comments in defense of the product, the number of urls they posted as reference and the professional language used to disprove your post; my gut tells me most come from the company themselves. They simply used your blog to their benefit; posting urls and mentioning the brand helps them improve their online scores with the search engines. This is why its so hard to find an honest or negative page talking about this and all other weightloss gimmicks. Next time don’t follow their lead.

– Dr. Suk Cho – Dr. Cho received his B.S. in Biochemistry at Juniata College, his M.S. in natural product chemistry at Miami University, and his Ph.D. in Organic Chemistry at Emory University. He has more than 30 patents and has authored or co-authored more than a dozen articles or abstracts in peer-reviewed scientific journals. Previously, Dr. Cho served on the Scientific Advisory Board or in upper-level management of R&D for a variety of nutrition-related companies. He was also R&D manager for global consumer product giant Unilever for nearly a decade.


This purifying broth contains fennel to help bile flow in your gallbladder; garlic to help with liver and gall bladder function; cabbage, excellent for detoxification in both the liver and kidneys; and shitake mushrooms to boost liver enzymes. Serve soup with a side of sauerkraut with sliced apples. Sauerkraut contains probiotics, the good bacteria that protect your GI tract. Make sure to use traditionally fermented sauerkraut to get the greatest health benefits. Apples boost both kidney and liver function.

Ditch the packaged, processed foods today (even the “healthy” versions). This will ensure you are taking out excess sodium, artificial ingredients and sugar from your diet. Also, ditch the salt shaker and instead use only herbs and spices to flavor your food. You’ll find this can help make a big difference in how you look and feel. Even after one day!
I suffered from severe Gluten and Irritable Bowel disease for years, over 5 in fact. And although i was being seen by my family doctor, nutritionists, and had completed all sorts of tests for Intestinal diseases no one was ever to fix me. I couldn’t leave the house without plotting out my route of every bathroom from point A to B, carried around plastic bags in case I needed to go and there was no bathroom around to make a stop at; I was also exhausted all the time, never had any energy. I lived a miserable life.
The average detox diet and cleanse lasts for a few days or weeks, but regular cellular cleansing, and using True Cellular Detox™ periodically, is a lifestyle change. Dramatic shifts in health may not occur overnight (though it’s possible), but cleansing at the cellular level is the only way to get real and lasting results in your health.If you are a certified natural health practitioner and are interested in integrating a true cellular detox system into your practice, please call 724.292.7673.
Very well said Tim Edge. Opinions and even some form of clinical information is fine, but at the end of the day what gives anyone the right to chastise others for choosing to walk a certain path in life? Oh and yes, medical practitioners can support, research, recommend and endorse all they like, that didn’t help the sufferers of thalidomide did it?
Actually, the information I provided isn’t “opinion” it’s fact, something Isagenix users have trouble grasping. Not ALL of the products are gluten-free, as I made very clear in the article. If you feel it works for you, great. But just because it helps you keep weight off doesn’t mean it’s keeping you healthy. Another thing I made very clear in the article.

Research on fasting’s effect on brain and mood has so far been done on animals, but the results are still promising. It appears that fasting stimulates the production of brain-derived neurotrophic factor (BDNF), which increases the resistance of brain neurons to degeneration and preserves learning and memory (5). Fasting has also shown to be beneficial in the brain for stimulating growth of new brain neurons, called neurogenesis (6). When levels of BDNF increase, so do levels of serotonin, otherwise known as the “feel good” neurotransmitter (7). This could help explain why one study among aging men found that after two-day fasts, their moods and perceptions of quality of life were improved (8).
What’s disconcerting to me is the culty behavior of all these Isagenix drones. “You must use Isagenix. Isagenix is like manna from the Gods. How dare you criticize it! It heals the world!” Blahblahblah. So annoying and anyone with half a thought in their brain could see through this rubbish. Dani, thanks for all you do and ignore the trolls. They are all brainwashed. I’m sure some people are “healed” and lost weight and cured of every disease under the sun but the fact of how they attack and defend and argue would make me run for the hills and never even consider their products. I know a few Isa-head drones in real life and every conversation is a ploy to get me to “just try the healthy lifestyle”, “just give it 30 days”, “don’t you want more energy?” blahblah and even one has gone so far as to say that my doctor who treats me via functional medicine and nutrition is robbing me of money and she wishes I could just try this program. Then she talks all about how much money she makes from the sales. I’m put off. I’m sticking with the ancestral nutrition route forever.
1. Millions of people on countries throughout the world have experienced profound reversals in the steady decline of their health due to the Isalean shakes. This is factual. There are, to date, no recorded cases of long-term users of the products experiencing a decline in their health. So, how can this be if the shakes contain toxic, rancid or other ingredients that are dangerous to one’s health? Here is the answer: Most people who reach for Isagenix as a system of overall health, weight loss, detoxification, etc., are people who have been addicted to simple carbohydrates, fast food, and the “typical” American diet, which as we know is way more toxic and carcinogenic than Isagenix. Most users of the product lose weight, and experience a dec rease in their CRPs, and other inflammation markers because the products are *replacing* frozen dinners, grab’n’go meals and snacks, vending machine “food,” and just about anything that can be purchased in a drive-through. While a micro- and macro-nutrient balanced, whole, organic food diet is by far a better option than any processed or fabricated meal replacement, the sad truth is that virtually every user of an Isagenix shake is incapable (for whatever reason, i.e., socioeconomic status, lack of understanding of food choices, peer pressure, lack of portability, etc.) of doing “better” than they have been — until they are told to simply consume 2 scoops of this powder twice a day. What I have seen, time and again, is constant improvement in health…and even the elimination of debilitating physical and emotional symptoms….when a person adhere’s to the Isagenix shakes, the cleanse liquid, and one meal per day of whole, preferably organic, macronutrient balanced foods. What I have seen, time and again, is that overweight people were consuming 1000s of empty calories of literally toxic food, yet were malnourished! Vitamin and mineral deficient, with leaky gut syndrome and the full gamut of dysbiosis-related syndromes and conditions.

This is an excellent and informative blog about Isagenix. I have some friends who, sadly have fallen for the “get healthy, get wealthy” brainwashing that Isagenix promotes. People are, or seem to be taught to push push push selling. If Isagenix is so interested in helping people, why not sell it to health stores, grocery stores etc? They exclusively use a pyramid sales model.
I actually read all of the comments and your responses to your review of Isagenix. Let me just state for all credential seekers out there, since that seems to be a recurring issue with them, I have M.D., NMD, and DC degrees. I am also board certified in Internal Medicine and triple board certified in clinical nutrition including the American Clinical Board of Nutrition and the Certification Board For Nutrition Specialists and btw I am a recovering MLMer.
But the products are expensive. I suspect too expensive, given that I can get protein shakes and similar “metabolism boosting” supplements at my local SuperSupplements store. My coach tells me that the difference in price is due to the “trace minerals” and the fact that the whey protein comes from fully organically raised cows in New Zealand. That sounds a bit fanciful to me, but I can’t ignore the fact that the system appears to work for me.
There are some vegetable oils contained in products however these are non-hydrogenated. Meaning they do not have trans fatty acids like hydrogenated oils do. Palm Kernel Oil is a stable vegetable oil that is extracted from the seed of Elaeis guineensis, the oil palm. Thriving in tropical areas, oil palm is commonly found in Southeast Asia and central Africa. Palm kernel oil is solid at room temperature, which is something that is unique for a plant-based oil. The reason is because of its high content in the medium-chain triglyceride lauric acid (similar to coconut oil).
I was connected to several people on FB that sell this product. They are all claiming the same ‘wealth’ that Isagenix has brought them. One girl claims she has purchased several expensive sports cars, fly’s in a private jet and has an expensive home (posting pictures to prove it). She also claims to be one of the top selling reps, yet her name is nowhere on the Isagenix website. Her pictures appear on other peoples pages as well. Her profile picture has changed from an older blonde woman to a young brunette. Sounds like a fraud to me. This is why I’ve started looking into this product. How can you trust it?
I recently read about the various P450 enzymes and their role in detoxifying our bodies…Could pesticides and additives have an adverse effect on these enzymes? I would love to see the research, but my instincts after reading more into the subject say perhaps. The question pertaining to this post concerning Isagenix supporting proper detoxification or not isn’t my point. My point is that the “old school” thinking of nutrition in the light of “every calorie is the same” needs to be thrown out. Isagenix at least supports people in making healthier choices…Kale instead of candy perhaps. You are what you eat, and heck, if Isagenix gets people to drink a nutritional shake vs eating a happy meal, I’m all for it.

@DrJonesy — thank you so much for your candor and perspective. I sense that is the experience many people have with Isagenix and other products. There isn’t a lot of proof they work, aside from a possible placebo effect which likely wears off. There is a risk they may in fact be bad for health. But the one thing we know for sure is that when you are selling a product via MLM, it tend to be overpriced, and it tends to be sold to people you care about, who buy it because they are about you and trust you. Thank you again for your story.


Wow. I was going to meet with one of the sales reps for this product until I read through this site and many others. So here’s my take: it’s probably not for me. I lead a relatively healthy lifestyle and try to eat organic when I can…but I am also very busy and dont always drive 45 mins to the farmers market or make my own protein shakes with raw eggs.
I was genuinely curious about Isagenix and its ingredients when I discovered your website as my wife has been using it for a few years now, thanks for the reminder that people justify eating whole foods don’t actually use any science to back up that belief. Word to the wise, any vitamins your body doesn’t use are excreted which at worst gives you expensive urine.
This article is well written and well informed. It’s actually a sad state of affairs that peoples diets are so bad that they have to turn to products like Isagenix for solutions and even worse that they get results, creating a vicious cycle of defending uninformed positions with confirmation bias. Isagenix is a prime example of how we can still avoid real nutritional science and capitalize off peoples desperation. It is clear that the ‘pro-Isagenix’ posts in this forum are either from people selling Isagenix products or those who feel they have to defend their position due to the great results they have had with isagenix fixing part of their nutrient deficiencies….. in the least efficient and unhealthiest way possible.
Juice diets do prevent your body from going into a state called ketosis, he says. Ketosis means your body has no carbohydrates to burn for energy, so it has to burn stored fat or whatever else is available, he tells WebMD. "You feel bad, even smell bad. That's what makes you feel like hell during a [water-only] fast. But is that because the toxins are coming out? No! You're going into ketosis. It's known physiology."
Many of the commenters seemed to think that doctors know nothing about nutrition. Doctors just put bandages on problems: they sell pills that mask symptoms and wreak havoc on your body instead of treating underlying causes. They only want to make money. They want to keep people sick so they won't lose their kickbacks. [What kickbacks?] There are lots of malpractice suits.
You speak specifically about Calcium D Pantothenate. This is also referred to as vitamin B-5 or pantothenic acid, is an essential nutrient your body uses to generate energy by breaking down carbohydrates and fats. Adults should consume at least 5 mg of calcium D-pantothenate each day to maintain a healthy body, according to the University of Maryland Medical Center. If you have trouble getting enough of this B-5 vitamin from your diet, your doctor may recommend treatment with a calcium D-pantothenate supplement.

A derivative of starch, maltodextrin is more easily digestible than other complex carbs, but it does not cause the same blood sugar spike associated with simple sugars. Semi-sweet or flavorless, this polysaccharide (chain of sugar units) comes from corn, tapioca, potato, wheat, or rice (1). Used as a thickening agent or to round out sweetness, maltodextrin is a white powder that is native to both home-cooking and packaged foods.
Hi Dani, I absolutely love your article. You are extremely knowledgeable. I hate everything to do with GMOs and Monsanto. I avoid processed and non organic foods and only buy local organic foods. I am a health and fitness coach and I try to steer my clients towards organic products. Recently I have been asked about this product and I knew very little on it. The only thing I knew was they claimed to be “Non GMO and Organic” I now know they are not. Isn’t it a shame that we have to worry about what is in our food? I am so glad I stumbled upon your article!! Best wishes!!

Just a year ago, a University of Illinois at Chicago College of Applied Sciences study comparing weight lost using Isagenix® versus a “heart-healthy” diet won a prestigious award from the American Society of Nutrition. The study was lead by Dr. Krista Varady, Ph.D., an Associate Professor and researcher at UIC. She’s contributed to more than 40 peer-reviewed publications and been featured on television, in print and in person as an authority on intermittent fasting for weight loss.
I would also like to share that I’m new to Isagenix (a couple weeks) AND I agree with you on some of the product ingredients. I even wrote an email to their support about their use of Palm Kernal Oil, not because of the ingredient itself, but because there’s a lot of controversy surrounding the areas where it’s grown. I’m not here to defend Isagenix. As I mentioned earlier, I agree. I read one comment earlier in which the person eluded to ISA as a transition. I would have to say that though it’s a shame some of these ingredients appear on some of the products, I’m happy to help some people take a step in the right direction. My mother for instance, addicted to coffee and sweets, can’t stand the thought of veggies, let alone raw and just in general practices poor eating habits. Yet, she’s feeling better already with ISA. Is it perfect? I’m not saying it is. I do hope, however, that it inspires her and other family members to continue on a path toward greater health and understanding of nutrition. But then, that’s not what what your blog post was about. It wasn’t created to argue the transitions of those in poorer health. It was simply created as an en devour into questionable ingredients. I will continue using it personally even, but I do so as part or a larger plan of general healthy eating practices. Are those practices perfect? No, sadly they aren’t. Personally, I’m doing the best I can, and the feedback I’m getting from family is that they’re feeling better. Is it a perfect solution? Again, nope, but it is a stepping stone towards one in my opinion. I will still also to encourage my family and friends to eat as organic as possible.

Dr. Harriet Hall writes more below about the junk science behind Isagenix. In short, there are no proven benefits to using the Isagenix products. Users of the products may offer anecdotes about their success with them, but that is not the same as having independent scientific studies supporting such claims. Of course, Isagenix prohibits reps from making medical claims about the products, but such a prohibition never seems to stop the distributors in any company.
I have actually taking Isagenix to a nutritionist and she told me how horrible it was. I even had it tested on me through Nutrition Response Testing ( NRT) and it was a fail, my body did not like it. So she is absolutely right. The stuff is pure crap. Do a standard process cleanse instead. The company is very reputable and only give accounts to nutritionist and nutrition student. That in it’s self tells you how good their products are. There is no pyramid scheme involved. Isagenix doesn’t care about your health they only want to make money that is why there products are crap. Synthetic vitamins are used and synthetic vitamins have been shown to cause disease ( ex. Synthetic vitamin E has been shown to increase your risk of heart disease where whole food vitamin E has been shown to decrease heart disease. See the difference. I have messed up my endocrine system from using things like herbal life and other “natural” weight loss supplements. I only take whole food supplements now.
You’ve obviously never tried it. You can spout off all the random information you want, but Isagenix makes me FEEL better than anything I’ve ever eaten. Something unhealthy could never make me feel this good. I’ve eaten whole, unprocessed, healthy foods my whole life, but my health completely turned around when I started adding Isagenix into the mix. Haters gonna hate, but you will NEVER, EVER convince me that Isagenix is unhealthy. It is the best thing I have ever done for myself. Cheers!
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